INFORMATION OF TAURINE an organic compound that is widely distributed in animal tissues.^[1] It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total human body weight. Taurine has many fundamental biological roles, such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling. It is essential for cardiovascular function, and development and function of skeletal muscle, theretina, and the central nervous system. Taurine is unusual among biological molecules in being a sulfonic acid, while the vast majority of biologically occurring acids contain the more weakly acidic carboxyl group. While taurine is sometimes called an amino acid, and indeed is an acid containing an amino group, it is not an amino acid in the usual biochemical meaning of the term, which refers to compounds containing both an amino and a carboxyl group.

USES OF TAURINESince the 2000s cosmetic compositions containing taurine have been introduced, possibly due to its antifibrotic properties. It has been shown to prevent the damaging effects ofTGFB1 to hair follicles.^[72] It also helps to maintain skin hydration.^[73]

Taurine is also used in some contact lens solutions.^[74]

• Taurine is used in the preparation of the anthelmintic drug netobimin (Totabin).
• Taurolidine
• Taurocholic acid & Tauroselcholic acid.
• Tauromustine
• Taurine

or2-aminoethanesulfonic acid, is anorganic compoundthat is widely distributed in animal tissues.^[1]It is a major constituent ofbileand can be found in thelarge intestine, and accounts for up to 0.1% of total human body weight. Taurine has many fundamental biological roles, such as conjugation ofbile acids,antioxidation,osmoregulation,membrane stabilization, and modulation ofcalcium signaling. It is essential forcardiovascularfunction, and development and function ofskeletal muscle, theretina, and thecentral nervous system. Taurine is unusual among biological molecules in being asulfonic acid, while the vast majority of biologically occurring acids contain the more weakly acidiccarboxyl group. While taurine is sometimes called an amino acid, and indeed is anacidcontaining anaminogroup, it is not anamino acidin the usual biochemical meaning of the term, which refers to compounds containing both anaminoand acarboxylgroup.

Taurine is named after theLatintaurus(acognateof theGreek) which meansbullorox, as it was first isolated from ox bile in 1827 by German scientistsFriedrich TiedemannandLeopold Gmelin.Taurine is involved in a number of crucial physiological processes. However, its role in these processes is not clearly understood and the influence of high taurine doses on these processes is uncertain. A substantial increase in the plasma concentration of growth hormone was reported in some epileptic patients during taurine tolerance testing (oral dose of 50 mg per kg body mass per day), suggesting a potential to stimulate the hypothalamus and to modify neuroendocrine function.^[60] A 1966 study found an indication that taurine (2 g/day) has some function in the maintenance and possibly in the induction of psoriasis.