Methyl 3-Aminocrotonate
₹2,600.00
Applications
Applications. Methyl 3-amino crotonate is used in synthesizing calcium channel blocking medicines utilized for treating hypertension. It is also used in the synthesis of Amlodipine Base and Amlodipine Besylate.
Description
Methyl 3-aminocrotonate is an intermediate in the synthesis of pyridinedicarboxylic acid. It is a white powder with a melting point of 160-165°C and a boiling point of 263°C. Methyl 3-aminocrotonate is soluble in water, alcohols, ethers, chloroform, and benzene.
Preparation
CONSTITUTION: Methyl acetoacetate is reacted with ammonia (1.5-4.0 mol ammonia to 1 mol methyl acetoacetate is pref.) in the presence of water (0.05-3.0 mol water to 1 mol methyl acetoacetate is pref.) in a temp. range of 35-70°C to obtain methyl 3-aminocrotonate.
Chemical Properties
Methyl 3-aminocrotonate is a chemical compound with properties related to its use as a precursor in organic synthesis, notably in the formation of various pharmaceutical and chemical compounds.
Definition
Methyl 3-aminocrotonate is an organic compound characterized by its structure containing an amino group, a methyl ester, and a conjugated double bond system, often used as a building block in organic synthesis.
Description
| Product Name | Methyl 3-Aminocrotonate |
| CAS Number | 14205-39-1 |
| Molecular Weight | 115.13 |
| Chemical Formula | C5H9NO2 |
| Melting point | 81-83 °C(lit.) |
| Boiling point | 112°C 42mm |
| Density | 1.1808 (rough estimate) |
| vapor pressure | 2.79-2.853hPa at 25℃ |
| refractive index | 1.4538 (estimate) |
| Flash point | 91 °C |
| storage temp | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | 18g/l |
| form | Crystalline Powder |
| pka | 5.27±0.70(Predicted) |
| color | White to slightly yellow |
| PH | 8-9 (18g/l, H2O, 20℃) |
| Water Solubility | insoluble |
| Sensitive | Hygroscopic |
| Packaging Size | As Per Requirement |
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