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Methyl 3-Aminocrotonate

Methyl 3-Aminocrotonate

Original price was: ₹2,700.00.Current price is: ₹2,600.00.

Applications

Applications. Methyl 3-amino crotonate is used in synthesizing calcium channel blocking medicines utilized for treating hypertension. It is also used in the synthesis of Amlodipine Base and Amlodipine Besylate.

Description

Methyl 3-aminocrotonate is an intermediate in the synthesis of pyridinedicarboxylic acid. It is a white powder with a melting point of 160-165°C and a boiling point of 263°C. Methyl 3-aminocrotonate is soluble in water, alcohols, ethers, chloroform, and benzene.

Preparation

CONSTITUTION: Methyl acetoacetate is reacted with ammonia (1.5-4.0 mol ammonia to 1 mol methyl acetoacetate is pref.) in the presence of water (0.05-3.0 mol water to 1 mol methyl acetoacetate is pref.) in a temp. range of 35-70°C to obtain methyl 3-aminocrotonate.

Chemical Properties

Methyl 3-aminocrotonate is a chemical compound with properties related to its use as a precursor in organic synthesis, notably in the formation of various pharmaceutical and chemical compounds.

Definition

Methyl 3-aminocrotonate is an organic compound characterized by its structure containing an amino group, a methyl ester, and a conjugated double bond system, often used as a building block in organic synthesis.

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Description

Product Name Methyl 3-Aminocrotonate
CAS Number 14205-39-1
Molecular Weight 115.13
Chemical Formula C5H9NO2
Melting point 81-83 °C(lit.)
Boiling point 112°C 42mm
Density 1.1808 (rough estimate)
vapor pressure 2.79-2.853hPa at 25℃
refractive index 1.4538 (estimate)
Flash point 91 °C
storage temp Keep in dark place,Inert atmosphere,2-8°C
solubility 18g/l
form Crystalline Powder
pka 5.27±0.70(Predicted)
color White to slightly yellow
PH 8-9 (18g/l, H2O, 20℃)
Water Solubility insoluble
Sensitive Hygroscopic
Packaging Size As Per Requirement

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