Melangestrol Acetate

650.00

Melengestrol acetate (MLGA), sold under the brand names Heifermax and MGA among others, is a progestin medication which is used in animal reproduction.[1][2] It is not approved for use in humans, and is instead used as an implantable contraceptive for captive animals in zoos and other refuges,[3] and is also used as a feed additive to promote growth in cattle, a purpose it is licensed for in the United States and Canada.

Uses

Animal reproduction

MLGA is used in animal reproduction.

Pharmacology

Pharmacodynamics

MLGA is a progestogen, and hence is an agonist of the progesterone receptor.[5] It has been found to possess 73% of the affinity of progesterone for the progesterone receptor in rhesus monkey uterus.

Description

Melengestrol acetate (17a-acetoxy-6-methyl-16-methylenepregna-4,6-diene-3,20-dione acetate; MGA) is a progestogen that is used as an animal feed additive to improve feed efficiency, increase the rate of weight gain, and suppress oestrus in beef heifers.

Trade names Heifermax, MGA
Other names MGA; MLA; MLGA; Melengesterol acetate; Methylsuperlutin; U-21240; BDH-1921; 17α-Acetoxy-16-methylene-6-methyl-6-dehydroprogesterone; 17α-Acetoxy-16-methylene-6-methylpregna-4,6-diene-3,20-dione
Drug class ProgestogenProgestinProgestogen ester
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.018.964 Edit this at Wikidata
Chemical and physical data
Formula C25H32O4
Molar mass 396.527 g·mol−1

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