Ibutilide Fumarate Inj

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Ibutilide fumarate activates slow inward sodium channels and thus is able to prolong the action potential duration and lengthen the refractory period of myocardial tissue. It was launched for the treatment of atrial fibrillation and flutter.

[Ibutilide Fumarate (100 mg)] – CAS [122647-32-9]

Description

Ibutilide fumarate is a medication used in the treatment of certain types of irregular heartbeats (arrhythmias), particularly atrial fibrillation and atrial flutter. It is often administered intravenously in a hospital setting. Here are some key points about Ibutilide Fumarate injection:

  1. Mechanism of Action:
    • Ibutilide works by affecting the electrical activity of the heart, specifically by prolonging the action potential duration and refractory period in atrial tissue. This can help restore normal heart rhythm.
  2. Indications:
    • Ibutilide is primarily used for the conversion of atrial fibrillation and atrial flutter to normal sinus rhythm.
  3. Administration:
    • Ibutilide fumarate is administered intravenously under medical supervision, usually as a single infusion.
    • The healthcare provider closely monitors the patient’s heart rhythm and vital signs during and after administration.
  4. Dosage:
    • The dosage and duration of infusion are determined by the healthcare provider based on the patient’s condition and response to the medication.
  5. Contraindications:
    • Ibutilide is generally contraindicated in patients with known hypersensitivity to the drug.
    • It may not be suitable for patients with certain pre-existing heart conditions or those at risk for certain arrhythmias.
  6. Monitoring:
    • Continuous monitoring of the patient’s heart rhythm and blood pressure is essential during and after the administration of ibutilide.
    • Electrocardiograms (ECGs) may be performed to assess the effectiveness of the treatment.
  7. Adverse Effects:
    • Common side effects may include nausea, headache, and chest pain.
    • Serious side effects such as arrhythmias or changes in blood pressure may occur and require prompt medical attention.
  8. Precautions:
    • Ibutilide should be used with caution in patients with certain heart conditions or a history of QT prolongation.
    • It may interact with other medications, so a healthcare provider should be aware of all the drugs a patient is taking.

It’s crucial for patients to inform their healthcare providers about their medical history, current medications, and any known allergies before receiving ibutilide fumarate. This information helps ensure the safe and effective use of the medication. This summary is for informational purposes only, and specific details should be obtained from a healthcare professional or prescribing physician.

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