Galactitol
₹500.00
Galactitol is an optically inactive hexitol having meso-configuration. It has a role as a metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite.
Description
| Molar Mass | 182.172 g/mol |
| CAS No | 608-66-2 |
| Formula | C6H14O6 |
Information of Galactitol:
Galactitol (dulcitol) is a sugar alcohol, the reduction product of galactose.[1] In people with galactokinase deficiency, a form ofgalactosemia, excess dulcitol forms in the lens of the eye leading to cataracts.[2]
Galactitol is produced from galactose in a reaction catalyzed by aldose reductase. Galactose itself comes from the metabolism of the disaccharide lactose into glucose and galactose.
The other common galactose metabolism defect is a defect in galactose-1-phosphate uridylyltransferase, an autosomal recessive disorder, which also causes a buildup of galactitol as a result of increased concentrations of galactose-1-phosphate and galactose. The toxicity associated with galactose-1-phosphate uridylyltransferase deficiency is associated with symptoms ofhepatosplenomegaly and mental retardation in addition to the cataracts caused by galactitol buildup.
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