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Cyanoacetamide

2,600.00

Applications

Cyanoacetamide is used in spectrofluorimetric methods to determine the activity of antihistamine H1 receptor antagonistic drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride.

Description

Cyanoacetamide is the starting reagent for vitamin B6 synthesis[1]. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes[2].

Preparation

Cyanoacetamide is prepared without additional catalyst by esterification of crude cyanoacetic acid with a monohydric alcohol which forms an azeotrope with water and has 4 to 10 carbon atoms, reacting the resulting ester with ammonia in the presence of a basic catalyst to give cyanoacetamide, and work-up by a mechanical

Chemical Properties

Cyanoacetamide exhibits various chemical properties, including its ability to participate in reactions such as nucleophilic addition, amidine formation, and condensation reactions, making it valuable in organic synthesis and pharmaceutical research.

Definition

Cyanoacetamide is a chemical compound with the formula C3H4N2O, consisting of a cyano group (-CN) attached to an acetamide moiety, and it is used in organic synthesis and as a reagent in chemical reactions.

Description

Product Name Cyanoacetamide
CAS Number 107-91-5
Chemical Formula C3H4N2O
Molecular Weight 84.08
Melting point 119-121 °C(lit.)
Boiling point 154.34°C (rough estimate)
Density 1,4 g/cm3
refractive index 1.5110 (estimate)
Flash point 419 °F
storage temp Sealed in dry,Room Temperature
solubility cold water: soluble1gm in 6.5ml
pka -1.27±0.10(Predicted)
form Crystalline Powder
color White to light cream
Odor Odorless
Packaging Size As Per Requirement

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