Atazanavir Sulphate
₹150.00
Applications
Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV).
Description
Atazanavir Sulfate is a sulfate salt form of atazanavir, an aza-dipeptide analogue with a bis-aryl substituent on the (hydroxethyl)hydrazine moiety with activity against both wild type and mutant forms of HIV protease. Atazanavir does not elevate serum lipids, a common problem with other protease inhibitors.
Preparation
According to an aspect of the present invention, there is provided a process for the preparation of Compound (A) that comprises preparing atazanavir sulphate by treating atazanavir base (Compound (II)) with sulphuric acid in a combination of solvents, and isolating Compound (A).
Chemical Properties
Atazanavir sulfate is a white to pale yellow crystalline powder with low solubility in water, known for its antiviral properties, and is a vital component in the treatment of HIV infection.
Definition
Atazanavir sulfate is a sulfated derivative of atazanavir, a protease inhibitor used in the treatment of HIV/AIDS by inhibiting the HIV protease enzyme.
Description
| Product Name | Atazanavir Sulphate |
| Brand | indian |
| Country of Origin | Made in India |
| Usage | Pharma |
| Formula | C38H54N6O11S |
| Molar Mass | 704.856 g/mol |
| CAS ID | 198904-31-3 |
| Elimination half-life | 6.5 hrs |
| Bioavailability | 68% |
| Molecular Weight | 802.94 |
| Melting point | 195.0°, or acetone; mp 198-199° (dec) |
| alpha | D22 -46.1° (c = 1 in 1:1 CH3OH/H2O, pH = 2.6) |
| storage temp | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | ≥28.7 mg/mL in DMSO with gentle warming; insoluble in H2O; ≥4.05 mg/mL in EtOH with gentle warming and ultrasonic |
| form | Powder |
| Packaging Size | As Per Requirement |
Our Export Location as a Atazanavir Sulphate Manufacturer, Supplier, Exporter, Stockist from India.
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