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Amitriptyline

Amitriptyline

Original price was: ₹3,000.00.Current price is: ₹2,600.00.

Applications

Amitriptyline is used to treat symptoms of depression. Amitriptyline is in a class of medications called tricyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance

Description

Amitriptyline is used to treat symptoms of depression. It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain. This medicine is a tricyclic antidepressant (TCA).

Preparation

Amitriptyline (7.1. 4) is synthesized by interaction of 10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]cyclohepten-5-one with 3-dimethylaminopropylmagnesium bromide and the subsequent dehydration of the resulting tertiary alcohol (7.1. 3) using hydrochloric acid [6–11].

Chemical Properties

Amitriptyline is a highly lipophilic molecule having an octanol-water partition coefficient (pH 7.4) of 3.0, while the log P of the free base was reported as 4.92. Solubility of the free base amitriptyline in water is 14 mg/L.

Definition

Amitriptyline is a tricyclic antidepressant medication used to treat various mental health conditions, primarily depression and neuropathic pain.

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Description

Product Name Amitriptyline
Country of Origin Made in India
Usage Pharma
Formula C20H23N
Molar Mass 277.403 g/mol
CAS No 549-18-8
Melting point 196-197°C
Flash point 11 °C
Category Small molecules
Purity ≥98%
MW 313.86
SMILES CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Solubility (25°C) Soluble in water, ethanol, DMSO
Storage Ambient
Storage Ambient
Packaging Size As Per Requirement

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