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Acetylcholine chloride

500.00

Acetylcholine is a direct-acting parasympathomimetic ophthalmic agent used to produce miosis during ophthalmic surgery. It is a naturally occurring neurohormone that helps transmit nerve impulses at all cholinergic sites including somatic and autonomic nerves.
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Description

CAS No 60-31-1
Formula (CH3)3N+CH2CH2OCOCH3Cl
Assay More than equal 99% (TLC)
Melting Point 146-150 Deg C(lit.)

Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with 7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-, IL-1, and IL-6.

 

 

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