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Abacavir Sulfate

Abacavir Sulfate

Original price was: ₹505,000.00.Current price is: ₹500,000.00.

Applications

Abacavir is an antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS.

Description

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.

Preparation

Stage-1 : N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide is reacted with (1S,4R)- 4-Amino-2-cyclopentene-1- methanol Tartrate, Sodium Carbonate in presence of Isopropyl Alcohol solvent media to get Stage-1 Compound.

Chemical Properties

Abacavir sulfate is a white crystalline powder with high solubility in water, known for its antiviral properties, targeting HIV reverse transcriptase, and often used in pharmaceutical formulations.

Definition

Abacavir sulfate is a pharmaceutical compound used in the treatment of HIV/AIDS, inhibiting the reverse transcriptase enzyme critical for viral replication.

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Description

Country of Origin Made in India
Usage Pharma
Formula C14H20N6O5S
Molecular Weight 384.41 g/mol
Storage Temperature 2-8degC
Physical Appearance A solid
Storage Store at -20°C
M.Wt 384.41
Cas No. 188062-50-2
Solubility insoluble in EtOH; ≥12.3 mg/mL in H2O; ≥8.63 mg/mL in DMSO with ultrasonic
Chemical Name [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid
Packaging Size As Per Requirement

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