2,4-Diamino-6-Hydroxypyrimidine
₹8,300.00
Applications
2,4-Diamino-6-hydroxypyrimidine is a selective inhibitor of GCH-I (GTP cyclohydrolase I). Suppression of this enzyme by 2,4-Diamino-6-hydroxypyrimidine impedes tetrahydrobiopterin biosynthesis and abolishes both lipopolysaccharide-induced elevation of biopterin levels and lipopolysaccharide-induced NO synthesis.
Description
2,4-Diamino-6-hydroxypyrimidine is a selective inhibitor of GCH-I (GTP cyclohydrolase I). Suppression of this enzyme by 2,4-Diamino-6-hydroxypyrimidine impedes tetrahydrobiopterin biosynthesis and abolishes both lipopolysaccharide-induced elevation of biopterin levels and lipopolysaccharide-induced NO synthesis.
Preparation
After the sodium has dissolved, the solution is cooled and 113 g. (1 mole) of ethyl cyanoacetate is added (Note 1). This mixture is allowed to stand while a second solution of sodium ethoxide of the same volume and concentration is prepared. To this solution is added 97 g.
Chemical Properties
2,4-Diamino-6-hydroxypyrimidine is a crystalline solid with potential reactivity at amino and hydroxyl groups, important in pharmaceutical synthesis as a building block for various drugs.
Definition
2,4-Diamino-6-hydroxypyrimidine is an organic compound with the chemical formula C4H6N4O, featuring a pyrimidine ring substituted with amino groups and a hydroxyl group, commonly used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals.
Description
| Product Name | 2,4-Diamino-6-Hydroxypyrimidine |
| CAS Number | 56-06-4 |
| Country of Origin | Made in India |
| Usage | Pharma |
| Formula | C15H14N2O2 |
| Molecular Weight | 254.28 g/mol |
| Manufacturer | Sihauli |
| Melting point | 285-286 °C (dec.) (lit.) |
| Boiling point | 234.22°C (rough estimate) |
| Density | 1.3659 (rough estimate) |
| refractive index | 1.7990 (estimate) |
| storage temp | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 10.61±0.50(Predicted) |
| form | Fine Crystalline Powder |
| color | White to cream |
| Sensitive | Light Sensitive |
| Packaging Size | As Per Requirement |
Our Export Location as a 2,4-Diamino-6-Hydroxypyrimidine Manufacturer, Supplier, Exporter, Stockist from India.
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