2-Iodobenzoic Acid
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Description
2-iodobenzoic acid and its derivatives are important pharmaceutical and chemical raw materials, which are necessary for the synthesis of various high-iodine reagents. It is commonly used as a precursor for the synthesis of 2-Iodoxybenzoic acid (IBX) and Dess-Martin peridinane, which are used as mild oxidants. It is also used in Suziki reaction.
Chemical Properties
white crystal powder. Soluble in alcohol and ether, insoluble in water.
Application:-
Reagent for detection of sulfhydryl groups in proteins. 2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.
Preparation
2-Iodobenzoic acid is obtained from Anthranilic acid by diazotization and substitution. Diazotization of Anthranilic acid with sodium nitrite in the presence of sulfuric acid, control the temperature below 10℃, filter the diazotization solution, add the mixture of potassium iodide and sulfuric acid, stir for 10min after addition, and boil. Filter, wash with sodium thiosulfate solution, 2-Iodobenzoic acid can be recrystallized from water.
Definition
ChEBI: An iodobenzoic acid with a single iodo substituent placed at the 2-position.
Description
2-Iodobenzoic Acid
2-Iodobenzoic acid, or o-iodobenzoic acid, is an organic compound with the formula IC6H4COOH. The synthesis of
2-Iiodobenzoic acid via the diazotization of anthranilic acid is a common performed in university organic chemistry labs.
Specifications – 2-Iodobenzoic Acid
Product | 2-Iodobenzoic Acid |
CAS No. |
88-67-5 |
Molecular formula | C7H5IO2 |
Molecular weight | 248.02 |
Descriptions | white to off-white powder. |
Melting range | Between 159° and 164°C |
Water | Max. 0.50% |
Purity | Min. 98.00% |
Packaging Size | As Per Requirement |
Grade Standard | Technical Grade |
Physical State | Powder |
MOLAR MASS | 248.018 |
DENSITY | 2.25 g/cm3 |
MELTING POINT | 162 °C |
INFROMATION OF 2-Iodobenzoic acid: 2-Iodobenzoic acid, or o-iodobenzoic acid, is an organic compound with the formula IC6H4COOH. The synthesis of 2-iodobenzoic acid via the diazotization of is commonly performed in university organic chemistry labs. One of its most common uses is as a precursor for the preparation of IBX and Dess–Martin periodinane, both used as mild oxidants.
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