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2-Iodobenzoic Acid

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Description

2-iodobenzoic acid and its derivatives are important pharmaceutical and chemical raw materials, which are necessary for the synthesis of various high-iodine reagents. It is commonly used as a precursor for the synthesis of 2-Iodoxybenzoic acid (IBX) and Dess-Martin peridinane, which are used as mild oxidants. It is also used in Suziki reaction.

Chemical Properties

white crystal powder. Soluble in alcohol and ether, insoluble in water.

Application:-

Reagent for detection of sulfhydryl groups in proteins. 2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.

Preparation

2-Iodobenzoic acid is obtained from Anthranilic acid by diazotization and substitution. Diazotization of Anthranilic acid with sodium nitrite in the presence of sulfuric acid, control the temperature below 10℃, filter the diazotization solution, add the mixture of potassium iodide and sulfuric acid, stir for 10min after addition, and boil. Filter, wash with sodium thiosulfate solution, 2-Iodobenzoic acid can be recrystallized from water.

Definition

ChEBI: An iodobenzoic acid with a single iodo substituent placed at the 2-position.

Description

2-Iodobenzoic Acid

2-Iodobenzoic acid, or o-iodobenzoic acid, is an organic compound with the formula IC6H4COOH. The synthesis of

2-Iiodobenzoic acid via the diazotization of anthranilic acid is a common performed in university organic chemistry labs.

 

Specifications – 2-Iodobenzoic Acid

Product 2-Iodobenzoic Acid
CAS No.

88-67-5

Molecular formula C7H5IO2
Molecular weight 248.02
Descriptions white to off-white powder.
Melting range Between 159° and 164°C
Water Max. 0.50%
Purity Min. 98.00%
Packaging Size As Per Requirement
Grade Standard Technical Grade
Physical State Powder
MOLAR MASS 248.018
DENSITY 2.25 g/cm3
MELTING POINT 162 °C

INFROMATION OF 2-Iodobenzoic acid: 2-Iodobenzoic acid, or o-iodobenzoic acid, is an organic compound with the formula IC6H4COOH. The synthesis of 2-iodobenzoic acid via the diazotization of is commonly performed in university organic chemistry labs. One of its most common uses is as a precursor for the preparation of IBX and Dess–Martin periodinane, both used as mild oxidants.

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