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1H-Benzimidazole-5-carboxylic acid

1H-Benzimidazole-5-carboxylic acid

Original price was: ₹2,500.00.Current price is: ₹2,400.00.

Applications

1H-Benzimidazole-5-carboxylic acid is utilized as a key intermediate in the synthesis of pharmaceuticals, including antifungal and antiviral agents, due to its benzimidazole scaffold with potential biological activities.

Description

1H-Benzimidazole-5-carboxylic acid is an organic compound with a benzimidazole ring and a carboxylic acid group, pivotal in pharmaceutical synthesis due to its versatile reactivity and potential pharmacological properties.

Preparation

Synthesis of 1-(4-methoxyphenethyl)-1H-benzimidazole-5-carboxylic acid derivatives was outlined in Scheme 1. 4-Fluoro-3-nitro-benzoic acid 1 was dissolved in dichloromethane (MDC). Methanol and thionyl chloride was added to it, and under reflux condition the compound 2 was formed.

Chemical Properties

1H-Benzimidazole-5-carboxylic acid is a crystalline solid with a characteristic benzimidazole structure, exhibiting stability and potential reactivity in various chemical reactions.

Definition

1H-Benzimidazole-5-carboxylic acid is an organic compound featuring a benzimidazole ring with a carboxylic acid group at the 5-position, significant in pharmaceutical synthesis and pharmacological research.

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Description

Product Name 1H-Benzimidazole-5-carboxylic acid
Chemical Formula C8H6N2O2
Molecular Weight 162.14
CAS No 15788-16-6
Melting point >300 °C (lit.)
Boiling point 288.82°C (rough estimate)
Density 1.3264 (rough estimate)
refractive index 1.5770 (estimate)
storage temp Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Powder
pka 3.10±0.30(Predicted)
color Green-gray to gray-brown
Packaging Size As Per Requirement

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