1H-Benzimidazole-5-carboxylic acid
Original price was: ₹2,500.00.₹2,400.00Current price is: ₹2,400.00.
Applications
1H-Benzimidazole-5-carboxylic acid is utilized as a key intermediate in the synthesis of pharmaceuticals, including antifungal and antiviral agents, due to its benzimidazole scaffold with potential biological activities.
Description
1H-Benzimidazole-5-carboxylic acid is an organic compound with a benzimidazole ring and a carboxylic acid group, pivotal in pharmaceutical synthesis due to its versatile reactivity and potential pharmacological properties.
Preparation
Synthesis of 1-(4-methoxyphenethyl)-1H-benzimidazole-5-carboxylic acid derivatives was outlined in Scheme 1. 4-Fluoro-3-nitro-benzoic acid 1 was dissolved in dichloromethane (MDC). Methanol and thionyl chloride was added to it, and under reflux condition the compound 2 was formed.
Chemical Properties
1H-Benzimidazole-5-carboxylic acid is a crystalline solid with a characteristic benzimidazole structure, exhibiting stability and potential reactivity in various chemical reactions.
Definition
1H-Benzimidazole-5-carboxylic acid is an organic compound featuring a benzimidazole ring with a carboxylic acid group at the 5-position, significant in pharmaceutical synthesis and pharmacological research.
Description
| Product Name | 1H-Benzimidazole-5-carboxylic acid |
| Chemical Formula | C8H6N2O2 |
| Molecular Weight | 162.14 |
| CAS No | 15788-16-6 |
| Melting point | >300 °C (lit.) |
| Boiling point | 288.82°C (rough estimate) |
| Density | 1.3264 (rough estimate) |
| refractive index | 1.5770 (estimate) |
| storage temp | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Powder |
| pka | 3.10±0.30(Predicted) |
| color | Green-gray to gray-brown |
| Packaging Size | As Per Requirement |
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