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Applications Applications. Methyl 3-amino crotonate is used in synthesizing calcium channel blocking medicines utilized for treating hypertension. It is also used in the synthesis of Amlodipine Base and Amlodipine Besylate. Description Methyl 3-aminocrotonate is an intermediate in the synthesis of pyridinedicarboxylic acid. It is a white powder with a melting point of 160-165°C and a boiling point of 263°C. Methyl…