Applications Adefovir dipivoxil is a nucleoside analogue used for chronic hepatitis B infection, including against lamivudine-resistant strains. It is administered as the oral prodrug (plasma t½ 8 h, intracellular t½ of active metabolite 17 h). Description Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for…