• 5-amino-2- Methyl Benzene Sulfonamide5-amino-2- Methyl Benzene Sulfonamide Quick View
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      5-amino-2- Methyl Benzene Sulfonamide5-amino-2- Methyl Benzene Sulfonamide Quick View

    • 5-amino-2- Methyl Benzene Sulfonamide

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    • Applications 5-Amino-2-methylbenzenesulfonamide is an intermediate for the synthesis of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR. Description 5-Amino-2-methylbenzenesulfonamide is an intermediate for the synthesis of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR. Preparation The invention relates to a preparation method of 2-methyl-5-aminobenzenesulfonamide, which comprises the following steps: s1 sulfonation: dissolving paranitrotoluene and chlorosulfonic acid…