Isobutyryl chloride (2-methylpropanoyl chloride) is the simplest branched-chain acyl chloride. It is found at room temperature as a corrosive, colorless liquid. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

DESCRIPTION

Isobutyryl chloride reacts with guanine to yield N(2)-isobutyrylguanine

Application

Isobutyryl chloride was used in the synthesis of fully isobutyramide terminated hyperbranched polyethylenimines[2]. It was used in the separation andidentification of shikonin and its ester derivatives in the root epidermis of Echium italicum L[3]. It was employed as versatile acylating agent for the ketimine derivatives of α-amino esters[4], nucleosides[5] and pyrroles[6].

Versatile acylating agent for the ketimine derivatives of α-amino esters,[4] nucleosides,[5] and pyrroles.[6]