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L – Pyroglutamic Acid

₹100.00

The most common uses of L-pyroglutamic acid deal with brain function due to its role in supporting the healthy production of neurotransmitters. L-pyroglutamic acid is often used to support memory and learning in addition to managing anxiety.
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Description

Physical State Powder
Usage Industrial
Grade Standard Technical Grade

CERTIFICATE OF ANALYSIS
PRODUCT NAME:L-PYROGLUAMIC ACID

CAS NO:98-79-3
FROMULA:

C5H7NO3


ASSAY:≥99.0% (T)
MOLAR MASS:129.12 g·mol−1
MELTING POINT:184 °C

INFORMATION OF L-PYROGLUAMIC ACID:Pyroglutamic acid is an uncommon and little studied amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam

Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon and little studied amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam.[1] It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. Pyroglutamate is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate. This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue
USES:The sodium salt of pyroglutamic acid – known either as sodium pyroglutamate, sodium PCA, or sodium pidolate – is used for dry skinand hair products, as it is a humectant. It has low toxicity and is not a skin irritant, but its use in products is limited by a high price.

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